An ELISA was performed using a serial dilution of HMGCR (Ser872) Polyclonal Antibody (bs-4063R) in antigen-coated wells. The antigen used was a peptide containing the phosphosite of interest. The plot shows the absorbance against the antibody dilution for phosphopeptide antigen and non-phosphorylated peptide antigen.

HMGCR Abs (3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase) are associated with necrotizing myopathy that is commonly related to statin exposure.

Diseases associated with HMGCR include Familial Hyperlipidemia and Sitosterolemia.Among its related pathways are Sterol Regulatory Element-Binding Proteins (SREBP) signalling and … HMGCR antibodies; LDLCQ3 antibodies; Custom Antibodies. If you can't find the antibody you're looking for, why not consider a custom reagent from one of these suppliers. View custom suppliers. Calculators. A collection of useful calculators with more to come!

Hmgcr antibody

Validated for Immunohistochemistry and Western Blot Anti-HMG-CoA reductase Antibody detects level of HMG-CoA reductase & has been published & validated for use in Immunoprecipitation, Western Blotting. - Find MSDS or SDS, a COA, data sheets and more information. Medium consistency between antibody staining and RNA expression data. Reliability score i A reliability score is manually set for all genes and indicates the level of reliability of the analyzed protein expression pattern based on available RNA-seq data, protein/gene characterization data and immunohistochemical data from one or several antibodies with non-overlapping epitopes. Anti-HMGCR antibody levels are reported to correlate with disease severity . However, they rarely, if ever, normalize even in patients that appear to have recovered fully .

Rabbit recombinant monoclonal HMGCR antibody [EPR1685(N)].

Antibody information for antibodies HPA008338 and CAB016797 used in analysis of ENSG00000113161 / HMGCR () We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies.

Blue: DAPI for nuclear staining. Rabbit anti-HMGCR Antibody. Rabbit polyclonal anti-HMGCR antibody (STJ24046) is suitable for use in Western Blot and Immunohistochemistry. Rabbit Polyclonal HMGCR antibody for IHC, WB. Published in 2 Pubmed References.

HMGCR antibody Rabbit Polyclonal from Proteintech validated in Immunohistochemistry (IHC), Immunofluorescence (IF),Enzyme-linked Immunosorbent Assay (ELISA) applications. This antibody reacts with human, mouse, rat samples.

We assessed anti-HMGCR antibodies in patients with suspected IMNM following statin exposure and patients with other autoimmune rheuma … Mouse monoclonal HMGCR antibody [CL0260]. Validated in WB, IHC and tested in Human.

Se hela listan på hopkinsrheumatology.org HMGCR Antibody: Chronic Myopathy, Young onset. VvG stain: Myopathic features Muscle fibers Internal architecture: May have aggregates Size: Varied HMGCR is a key enzyme in cholesterol biosynthesis. Anti‐HMGCR antibodies are considered relatively specific for necrotizing myositis and are usually associated with statin exposure 12, 13. As a single case report, the presented clinical and laboratory findings can only be considered hypothesis generating.

2010 Sep;62(9):2757-66. doi: 10.1002/art.27572). Invitrogen Anti-HMGCR Polyclonal, Catalog # PA5-37367.
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IMNM har stark association med SRP och HMGCR-antikroppar. SYMTOM. Skelettmuskel Myositer utvecklas akut, subakut eller långsamt och leder till uttalad

Anti-HMGCR antibodies were measured by two ELISA tests (one home-made, one commercial) and confirmed by presence of anti-HMGCR antibody and confirm the diagnosis of HMGCR IMNM. Clinical studies have shown that disease severity, as measured by muscle Buy rabbit polyclonal antibody to HMGCR (A88049). Applications: WB, IHC and IF. Reactivity: Human and Rat. ✔️ 100% Guarantee ✔️ FREE Shipping. Apr 1, 2017 In addition to NAM, anti-HMGCR antibodies are associated with statins, an intriguing finding given that HMGCR is the pharmacologic target of Nov 25, 2019 a diagnostic alert that anti-HMGCR related immune mediated necrotizing myopathy should (HMGCR) antibody, which was strongly positive.

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Anti-HMGCR antibodies are offered by a number of suppliers. This target gene encodes the protein '3-hydroxy-3-methylglutaryl-CoA reductase' in humans and may also be known as LDLCQ3, 3-hydroxy-3-methylglutaryl-Coenzyme A reductase, and 3-hydroxy-3-methylglutaryl CoA reductase (NADPH).

It is unclear whether anti‐HMGCR IgG antibodies to 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) are mainly associated with necrotizing autoimmune myopathy (NAM) in a subset of statin-treated patients. Although infrequent, these antibodies may also be observed in statin-naive patients with NAM. 2020-08-13 HMGCR : Evaluating patients with suspected necrotizing autoimmune myopathy Measuring 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) antibodies 2020-01-08 HMGCR antibody Rabbit Polyclonal from Proteintech validated in Immunohistochemistry (IHC), Immunofluorescence (IF),Enzyme-linked Immunosorbent Assay (ELISA) applications.